Furosemide Tablets are a potent 'loop' diuretic used in the treatment of oedema resulting from cardiac insufficiency, hepatic or renal dysfunction, parasitism, or of a traumatic origin. They are most commonly used as part of the medical management of congestive heart failure and other conditions where the body is retaining too much fluid.
Furosemide Tablets are flat faced, white circular tablets with bevelled edges. They are scored with a half break line for accurate dosing.
£0.08Furosemide Tablets 20mg are indicated for the treatment of oedema associated with cardiac insufficiency, renal dysfunction, and trauma in cats and dogs. Furosemide is the most commonly used...
Furosemide Tablets 40mg are indicated for the treatment of oedema associated with cardiac insufficiency, renal dysfunction, and trauma in cats and dogs.
Contra-indicationsDo not use in acute glomerular nephritis, in electrolyte diseases, in patients with anuria, or patients that have received excessive doses of cardiac glycosides. Because of the danger of potentiating their toxic effects do not use with aminoglycoside or cephalosporin antibiotics. Allergic reactions have been associated with use with sulphonamides.
Special WarningsThe patient may increase its water intake to compensate for the diuresis. Consideration should be given to restricting water intake if the patient's condition makes such a course appropriate.
Special PrecautionsSpecial precautions for use in animals:Prolonged dosage may on occasions justify potassium supplementation and thus monitoring for hypokalaemia should be considered, especially if the product is used in conjunction with cardiac glycosides.Special precautions to be taken by the person administering the medicinal product to animals:Wear gloves or wash hands immediately after handling tablets. In case of accidental ingestion seek medical attention and show product label and/or pack insert to the doctor.
Adverse ReactionsNone reported
Pregnancy and LactationThe safety of use in pregnancy is not well established and a careful assessment of the likely benefits and potential risks should be made. A deleterious effect on lactation is to be expected, particularly if drinking water is restricted. Furosemide passes into milk, but not to a great extent.
InteractionsPotential interactions with other drugs include ototoxicity with aminoglycosides and nephrotoxicity with cephalosporins. Use in combination with sulphonamide treatment may lead to sulphonamide allergy. There is a possibility of interaction with cardiac glycosides.
Amounts to be Administered and Administration Route5mg/KgBW, one or two times per day. For patients weighing less than 8Kg dosage with the 20mg tablet (which may be halved) is recommended. Avoid overdosage in weak and old patients.
OverdoseDehydration and electrolyte depletion may occur. Monitor and correct, as necessary. Dosage higher than that which is recommended, may cause transitory deafness. Cardiovascular side effects may be observed in weak and old patients following overdose.
Withdrawal PeriodsNone for these species.
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Furosemide is a loop diuretic that is used to treat fluid retention (edema) caused by heart failure, liver disease, or kidney problems. It belongs to a class of drugs called thiazolidinediones and works by increasing the amount of urine produced by the kidneys. This helps to lower the production of salt and water in the body, which helps to relieve symptoms such as swelling and fluid retention.
Furosemide is available in tablet form and is usually taken once daily or as an injection into the vein or muscle. It can be given via a pump or an oral route. The usual starting dose for adults is 20 mg. The dosage is based on your medical condition and response to treatment. Your doctor will determine the dose and duration of the medication based on your specific needs.
Uses
Furosemide is primarily used to treat edema (fluid retention) caused by heart failure, liver disease, or kidney problems.
Furosemide works by blocking the reabsorption of sodium and chloride in the kidneys, leading to increased urine production. This can help alleviate symptoms such as swelling, fluid retention, and difficulty urinating.
It is important to follow your doctor’s instructions regarding the dosage and duration of treatment. If you have kidney problems, your doctor may adjust your dosage or suggest additional adjustments based on your medical condition and response to treatment. Your doctor can help you determine the best course of treatment for your condition.
Furosemide can also be used to treat hypercalcemia (high levels of calcium in the blood). Your doctor may start you on a low dose of furosemide and gradually increase it as necessary. Your doctor may prescribe a lower dose of furosemide to reduce the risk of side effects, such as electrolyte imbalances. Your doctor can monitor you closely for signs and symptoms of hypercalcemia or hypernatremia (high levels of calcium in your blood).
This medication can be given by injection in the vein or muscle. Your doctor will determine the dose and duration of treatment based on your specific needs.
Furosemide can be taken in tablet form. It is available in the form of a 10 mg, 20 mg, and 40 mg tablet.
How it works
Furosemide works by blocking the reabsorption of sodium and chloride in the kidney tubules. This leads to increased urine production, which helps to relieve symptoms of fluid retention and swelling. Furosemide can be given via a pump or an oral route.
The medication helps to relieve symptoms of edema caused by heart failure, liver disease, or kidney problems.
The medication works by blocking the reabsorption of sodium and chloride in the kidneys, which leads to increased urine production. This can help to relieve symptoms of fluid retention and swelling.
Important safety considerations
Furosemide should not be taken by people who have certain medical conditions or who are taking certain medications. Before starting furosemide, tell your doctor if you have kidney or liver problems, high blood pressure, or if you are taking certain medications. Your doctor may need to adjust your dosage or prescribe additional adjustments based on your medical condition and response to treatment.
Your doctor may need to change your dose or monitor you closely for signs and symptoms of hypercalcemia (high levels of calcium in your blood).
Furosemide can cause low potassium levels (hypokalemia) in the body, leading to weakness and depression. Your doctor may need to adjust your dosage or monitor you closely for signs and symptoms of hyperkalemia (high levels of potassium in your blood).
1. KD. Tripathi. Diuretics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 579-581.
2. Robert F. Reilley and Edwin K. Jackson. Regulation of renal function and vascular volume. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 682-686.
3. University of Pennsylvania. Furosemide for Accelerated Recovery of Blood Pressure Postpartum (ForBP). NIH U. S. National Library of Medicine ClinicalTrials.gov. [Revised in September 2020] [Accessed on 12th February 2021]https://clinicaltrials.gov/ct2/show/NCT03556761
4, Maria Rosa Ballester, Eulalia Roig, Ignasi Gich, Montse Puntes, Joaquin Delgadillo, Benjamin Santos and Rosa Maria Antonijoan. Randomized, open-label, blinded-endpoint, crossover, single-dose study to compare the pharmacodynamics of torasemide-PR 10 mg, torasemide-IR 10 mg, and furosemide-IR 40 mg, in patients with chronic heart failure. NCBI; PMC US National Library of Medicine, National Institute of Health. August 2015. [Accessed on 12th February 2021]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532344/
5. Elara Pharmaservices Limited. Electronic Medicines Compendium (EMC). [Revised in October 2020] [Accessed on 12th February 2021]https://www.medicines.org.uk/emc/files/pil.12129.pdf
6. Clonmel Healthcare Ltd. Health Products Regulatory Authority (HPRA). [Revised in December 2016] [Accessed on 12th February 2021]https://www.hpra.ie/img/uploaded/swedocuments/2188112. PA0126_008_002.fbf0465a-d44d-4c59-b51b-337dd8586c8e.000001Product%20Leaflet%20Approved.170215.pdf
All data, materials and opinions are owned by the 58-year-old Pharmaservice Limited, which is the triad of comprarapid Drugs, estacids, quinidine and sodium-glucose Chennai, Chennai, India. 85% of the data was presented in a peer-reviewed journal. This is no different to many similar product quality issues where high ratings are given in the scientific press. The data presented in this article is from the NCBI International Non-Invasive Treatment of Ed (NITIE) ClinicalTrials.gov database, which has been approved by the U. Food and Drug Administration. It is accessible through the link below: [Accessed on 12th February 2021]https://www.nci.com/NCBI/NITIE/NCBI2021/NCBI40/NITIE40.htmMarch 2015. Page – 759-581.
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Furosemide is a loop diuretic used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. Furosemide is also used to treat high blood pressure (hypertension).
Furosemide works by increasing the amount of urine the body makes, which helps reduce swelling and symptoms of fluid retention and helps lower high blood pressure. Furosemide tablets are sometimes called water pills as they increase how much you urinate.
Before using this medicine, tell your doctor if you have kidney disease, enlarged prostate, urination problems, cirrhosis or other liver disease, an electrolyte imbalance, high cholesterol, gout, lupus, diabetes, or an allergy to sulfa drugs.
Tell your doctor if you have recently had an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into your veins. Do not take more of this medication than is recommended.
If you are being treated for high blood pressure, keep using this medicine even if you feel fine. High blood pressure often has no symptoms.
Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose schedule must be adjusted to the individual patient’s needs
Tell your doctor about all your other medicines. Some drugs should not be used with furosemide.
It is not known if furosemide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breastfeed while using furosemide. Ask your doctor about any risk. Furosemide may slow breast milk production.
Oral: Initial dose: 20 to 80 mg orally once; may repeat with the same dose or increase by 20 or 40 mg no sooner than 6 to 8 hours after the previous dose until the desired diuretic effect has been obtained. Maintenance dose: Administer the dose that provided the desired diuretic effect once or twice a day (e.g., at 8 am and 2 pm).
Common side effects:
Do not use:
is a side effect of this medicine. It is usually mild and temporary. It usually causes a decrease in urine output but may also cause loss of appetite. If experienced by a child who is about to be born, or who is about to be born at the first sign of a lack of appetite, seek medical advice immediately. It is not known if this side effect is permanent.
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